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Allele : Drd2<tm2Ebo> dopamine receptor D2; targeted mutation 2, Emiliana Borrelli

Primary Identifier  MGI:2675755 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Drd2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 6 was replaced with a neomycin selection cassette in order to selectively delete the long isoform of the receptor expressed from this gene. RNAse protection assays demonstrated that the short isoform expression is up-regulated in homozygotes and long isoform expression is undetectable.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • D2L -,
  • D2L -,
  • D2-,
  • D2-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele