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Allele : Tg(Tyr-HRAS)60Lc transgene insertion 60, Lynda Chin

Primary Identifier  MGI:2676096 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Tyr-HRAS)60Lc
Strain of Origin  (C57BL/6J x CBA/J)F1 Is Recombinase  false
Is Wild Type  false
description  Transgenic animals were produced from two founders, TR39 and TR60, that possessed low transgene copy number and expression level. In TR60, the transgene had inserted into the Y chromosome.
molecularNote  The mutant human H-Ras (G12V) has been placed under the control of the tyrosinase promoter and distal enhancer followed by the SV40 splice and polyadenylation sequences. Transgene copy number is low and integration was on the Y chromosome.
  • mutations:
  • Insertion
  • synonyms:
  • Tyr-RAS,
  • Tyr-RAS
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

17 Publication categories

Trail: Allele