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Allele : Irak4<tm1Yeh> interleukin-1 receptor-associated kinase 4; targeted mutation 1, Wen-Chen Yeh

Primary Identifier  MGI:2676448 Allele Type  Targeted
Attribute String  Null/knockout Gene  Irak4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2, which contains the start codon, was replaced with a neomycin selection cassette inserted by homologous recombination. Although mutant transcript was detected by RT-PCR analysis using C-terminal primers, neither normal nor truncated protein was undetected by Western blot analysis of MEFs derived from homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Irak-4<->,
  • Irak-4<->,
  • IRAK<->,
  • IRAK-4 KO,
  • IRAK-4 KO,
  • IRAK<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

21 Publication categories

Trail: Allele