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Allele : Thrb<tm4Few> thyroid hormone receptor beta; targeted mutation 4, Frederic E Wondisford

Primary Identifier  MGI:2676951 Allele Type  Targeted
Attribute String  Null/knockout Gene  Thrb
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was replaced with a self-excising PGK-neo cassette. The deletion of exon 3 putatively results in an aberrant open reading frame caused by the fusion of exons 2 and 4. Using a C-terminal mAb, protein was undetected by Western blot analysis of homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • TR-Beta<->,
  • TRbetaKO,
  • TR-Beta<->,
  • TRbetaKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele