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Allele : Ptprz1<tm1Mno> protein tyrosine phosphatase receptor type Z, polypeptide 1; targeted mutation 1, Masaharu Noda

Primary Identifier  MGI:2678757 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ptprz1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing lacZ and neo was inserted just downstream of the start codon in exon 1, such that the first 4 codons, which encode the signal peptide, were left intact. Protein was undetected in brain tissue of homozygous mutant mice by Western blot analysis using an antibody targeted against the endogenous extracellular domain. LacZ expression was verified by X-gal staining.
  • mutations:
  • Insertion
  • synonyms:
  • PTPZeta<->,
  • PTPZeta<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

18 Publication categories

Trail: Allele