Primary Identifier | MGI:2677450 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Th-cre)12Mrub |
Strain of Origin | (C57BL/6 x CBA)F2 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | Sequence encoding cre recombinase was adjpoined to 9 kb of the rat tyrosine hydroxylase (Th) promoter. The rat Th promoter sequence drove expression of cre recombinase in catecholaminergic neurons. Expression was observed in the olfactory bulb, hypothalamic and midbrain dopaminergic neurons, the locus coeruleus, amacrime neurons of the retina, chromaffin cells of the adrenal medulla, and sympathetic ganglia. |