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Allele : Hif1a<tm1.1Stom> hypoxia inducible factor 1, alpha subunit; targeted mutation 1.1, Shuhei Tomita

Primary Identifier  MGI:2677899 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hif1a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 13, 14, and 15 were deleted by cre-mediated recombination of flanking loxP sites. The deleted region encoded the C-terminal transactivation domain that is involved in response to hypoxia, Cri2 recruitment, and efficient nuclear localization. Though a truncated protein consisting was detected, it was reported to be non-functional.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Hif-1alpha<delta>,
  • Hif-1alpha<delta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele