| Primary Identifier | MGI:2680322 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Gba1 |
| Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked neomycin resistance gene was inserted into intron 8 and a G-to-C point mutation was created at position 1320 (GenBank M24119) in exon 9 causing a V-to-L amino acid substitution at residue 412 (394 in mature protein) (p.V412L). The neo cassette was then removed through subsequent Cre-mediated recombination. |
