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Allele : Tg(rPEPCKSREBF2)788Reh transgene insertion 788, Robert E Hammer
Primary Identifier  MGI:2680523 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(rPEPCKSREBF2)788Reh
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene is composed of the rat Pepck promoter fused to a cDNA encoding amino acids 1-468 of human SREBP-2 followed by 2 stop codons. The 2.4 kb rat Pepck promoter is active in liver and adepose tissue. The cDNA portion encodes the 6HLH-zip domain and the NH2-terminal acidic transactivation domain. It lacks the membrane attachment domain and the COOH-terminal regulatory domain. Production of truncated product was determined by immunoblot analysis.
  • mutations:
  • Insertion
  • synonyms:
  • Line B,
  • Line B
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

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0 Driven By

12 Publication categories

Trail: Allele




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