|  Help  |  About  |  Contact Us

Allele : Pdgfrb<tm10Sor> platelet derived growth factor receptor, beta polypeptide; targeted mutation 10, Philippe Soriano

Primary Identifier  MGI:2682393 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pdgfrb
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  A frameshift mutation was generated at codon 780, resulting in a nonsense mutation at 801. This stop codon is 11 residues downstream of the RasGAP binding site and precludes the translation of the SHP-2 and PLC-gamma binding sites.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Beta<T>,
  • Beta<T>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele