| Primary Identifier | MGI:2680328 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Gba1 |
| Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked neomycin resistance gene was inserted into intron 8 and an A-to-T point mutation was created at position 1366 (GenBank M24119) in exon 9 causing a D-to-V amino acid substitution at residue 427 (409 in mature protein) (p.D427V). The neo cassette was then removed through subsequent Cre-mediated recombination. |
