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Allele : Grxcr1<pi-tde> glutaredoxin, cysteine rich 1; tasmanian devil

Primary Identifier  MGI:2681910 Allele Type  Transgenic
Gene  Grxcr1 Inheritance Mode  Recessive
Strain of Origin  (C57BL/6J x CBA/Ca)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Multiple copies of a transgenic construct, consisting of the Roux Sarcoma Virus promoter adjoined to the entire coding region of the human placental alkaline phosphatase gene, inserted in tandem array in the middle of chromosome 5. Phenotypic characteristics segregated with transgene and were not observed in a different line with similar levels of expression, indicating the phenotype was largely due to the site of insertion. A non-complementation test demonstrated that the insertional mutation is allelic to pirouette. Further molecular analysis showed that the insertion is located in intron 1, 32 kb upstream of exon 2.
  • mutations:
  • Insertion
  • synonyms:
  • PLAP26,
  • PLAP26
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele