| Primary Identifier | MGI:2682958 | Allele Type | Targeted |
| Gene | Hbegf | Transmission | Germline |
| Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Point mutations were introduced in the cDNA sequence which transformed the amino acids residues at positions 148-149 from Leu-Pro to Ser-Thr. The modified cDNA sequence was then fused to the start codon of exon 1 along with IRES, a neomycin resistance gene and a polyadenylation sequence. It is predicted that the resulting product would not be cleavable to release the soluble form of the protein. |
