Primary Identifier | MGI:2683025 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ecsit |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A single loxP site remained in place of exons 2 through 8 after homologous recombination of floxed neo cassette and its subsequent cre-mediated excision. The deleted region included exons 2 through 5, which are common to the three known splice variants. Protein was undetected in homozygous mutant ES cells by Western blot analysis. |