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Allele : Nkx1-1<tm1Tlu> NK1 homeobox 1; targeted mutation 1, Thomas Lufkin

Primary Identifier  MGI:2684149 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nkx1-1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The sequence at the end of exon 2 and at the beginning of intron 2 was replaced with an IRES-lacZ and floxed neomycin resistance gene. This results in the production of a truncated, non functional protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele