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Allele : Pax3<tm1Buck> paired box 3; targeted mutation 1, Margaret E Buckingham

Primary Identifier  MGI:2687297 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pax3
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  A 3' portion of exon 2 was replaced with a cassette containing IRES-lacZ followed by a polyadenylation signal. The targeting vector contained a floxed puromycin resistance gene, however this was excised via cre mediated recombination, leaving only a single loxP site following the lacZ cassette. The expression pattern of lacZ was shown to be similar to that of the endogenous gene.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pax3<nLacZ>,
  • P34TKZ Pax3 reporter,
  • Pax3<ILZ>,
  • Pax3<ILZ>,
  • Pax3<->,
  • Pax3<IRESnLacZ>,
  • P34TKZ Pax3 reporter,
  • Pax3<nLacZ>,
  • Pax3<IRESnLacZ>,
  • Pax3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

27 Publication categories

Trail: Allele