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Allele : Fgf8<tm3Mrc> fibroblast growth factor 8; targeted mutation 3, Mario R Capecchi
Primary Identifier  MGI:2686826 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph, Reporter Gene  Fgf8
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  This hypomorphic allele was generated by inserting an frt-flanked neomycin cassette into intron 5. Single loxP sites located in introns 4 and 5, flank exon 5 and the neomycin cassette. An alkaline phosphatase gene was inserted just 5' to the second lox P site such that upon cre-mediated recombination, the alkaline phosphatase gene is expressed under the control of the Fgf8 gene. Fgf8tm1Mrc and Fgf8tm2Mrc were respectively generated by cre- and flp-mediated recombination of this allele.
  • mutations:
  • Insertion
  • synonyms:
  • Fgf8<H>,
  • Fgf8<CR>,
  • Fgf8<H>,
  • Fgf8<APN>,
  • Fgf8<hy>,
  • Fgf8<APN>,
  • Fgf8<hy>,
  • Fgf8<CR>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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11 Publication categories

Trail: Allele




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