| Primary Identifier | MGI:2686850 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Del(11Jmjd6-Mettl23)1Flv |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The first 2 exons were replaced with a neomycin resistance gene. Absence of expression after this gene modification was confirmed by Northern blot analysis. A subsequent publication demonstrated that the targeting vector also replaced the first exon of the neighboring gene Mettl23, located on the opposite strand. RT-PCR confirmed absence of Mettl23 mRNA in homozygous embryos. |
