| Primary Identifier | MGI:3028797 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Pnpla6 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cassette containing IRES-lacZ and neo was inserted at codon 397, upstream of the carboxyl-terminal catalytic domain. Western blot analysis of lysates from cultured cells indicated an absence of protein of in homozygous mutant embyros. A 50% reduction of esterase activity in tissue homogenates obtained from heterozygous mutant mice indicated functional ablation. |
