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Allele : Actc1<tm1.1Buck> actin, alpha, cardiac muscle 1; targeted mutation 1.1, Margaret E Buckingham

Primary Identifier  MGI:3029177 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Actc1
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encoding mutated nuclear localized lacZ with intragenic duplication corresponding to nucleotides 870-1987 after the ATG such that a shift in codon phase introduces a TGA STOP codon at nucleotide 1993 was inserted immediately after the start codon via homologous recombination. A floxed neo cassette included in the targeting vector was excised via cre-mediated recombination. The expression pattern of lacZ recapitulated that of the endogenous gene.
  • mutations:
  • Insertion
  • synonyms:
  • alphac-actin<nlaacZ1.1delta>,
  • alphac-actin<nlaacZ1.1delta>,
  • alphac-actin<nlaacZ1.1>,
  • alphac-actin<nlaacZ1.1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele