Primary Identifier | MGI:3029983 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | Runx1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cDNA encoding the entire RUNX1 protein was inserted into exon 4 of the endogenous locus via homologous recombination. Semiquantitative RT-PCR analysis of splenic and thymic message showed the levels of mutant transcript in homozygous mutant mice to be similar to the levels of normal transcript in wild-type mice. |