Primary Identifier | MGI:3033224 | Allele Type | Chemically induced (ENU) |
Gene | Gck | Inheritance Mode | Dominant |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | RIKEN GSC ENU Project |
molecularNote | G to A transition in exon 6 results in a missense mutation and substitution of tyrosine for cysteine at amino acid 220. Real time PCR detected no change in Gck mRNA expression however protein levels and Gck activity are reduced. |