| Primary Identifier | MGI:3037293 | Allele Type | QTL |
| Gene | Idd1 | Inheritance Mode | Not Specified |
| Strain of Origin | NOD/Uf | Is Recombinase | false |
| Is Wild Type | false |
| description | NOD is homozygous for recessive alleles for susceptibility at all three loci, Idd1s, Idd2s, and Idd3s. The dominant alleles for non-susceptibility to IDD, Idd1r, etc., occur in the NON strain. Homozygosity for the recessive alleles at all three loci is necessary for the development of IDD.The Idd1 locus is linked to the major histocompatibility locus on Chr 17, but Idd2 is on Chr 9 (1) and Idd3 is on Chr 3 (J:8783, J:3351). This locus is also linked to peripheral CD4 lymphocytosis. |
| molecularNote | This allele confers increased periinsulitis and increased CD4 lymphocytosis compared to C57BL/6. |
