Primary Identifier | MGI:3038670 | Allele Type | QTL |
Gene | Ath19 | Inheritance Mode | Not Specified |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
description | Ath18 and Ath19 interact. Homozygosity for C57BL/6J-derived alleles at Ath18 in conjunction with 129S1/SvImJ-derived alleles at Ath19 confers susceptibility to atherosclerosis. Homozygosity for 129S1/SvImJ-derived alleles at Ath18 in conjunction with homozygosity for C57BL/6J-derived alleles at Ath19 also confers atherosclerosis susceptibility. Wang et al (J:140288) detected Ath19 in Apoetm1Unc homozygous F2 animals. |