Primary Identifier | MGI:3039777 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Mt1-RET)304Ina |
Strain of Origin | (BALB/c x C57BL/6) X BALB/c | Is Recombinase | false |
Is Wild Type | false |
description | Founder only. Lines 304a, 304b, and 304c were derived from this mouse. Additional founder numbers: 108, 192, 207, 242, 301, 319. |
molecularNote | Human RET proto-oncogene cDNA driven by the mouse metallothionein 1 promoter/enhancer. This mouse is predicted to have 5 copies of the transgene. Northern blot analysis revealed high levels of transgene expression in tumors and varying levels in melanin-producing cells of other tissues in mice of this line, including skin, muscle and Harderian glands. |