Primary Identifier | MGI:3040431 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Setdb1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 15-22 were replaced with an IRES-betageo cassette. These exons encode the pre- and post-SET catalytic region of the protein, and removal was predicted to abolish all activity. X-gal staining detected lacZ expression in homozygous embryos. |