| Primary Identifier | MGI:3040869 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Klhl10 |
| Transmission | Chimeric | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| description | Haploinsufficiency of Klhl10 in male chimeras prevents genetic transmission of the mutated allele from males and increases the difficulty of generating non-chimeric heterozygous mice. Phenotype data reported are from chimeric male mice and a single heterozygous male generated from a female chimera. |
| molecularNote | Exon 1, containing the start codon, was deleted via homologous recombination. Northern blot analysis showed decreased expression in heterozygous stem cells. |
