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Allele : Arnt<tm1Bra> aryl hydrocarbon receptor nuclear translocator; targeted mutation 1, Christopher A Bradfield

Primary Identifier  MGI:3042111 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Arnt
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A global hypomorphic Arnt allele was generated by inserting a neo cassette flanked by Loxp sites 3' of exon 6, which encodes the basic helix-loop-helix domain. A third loxp site was inserted 5' of exon 6. Western blot analysis confirmed decreased Arnt expression in all tissues examined from homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • Arnt<3lox>,
  • Arnt 3-lox,
  • Arnt<3lox>,
  • Arnt 3-lox
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele