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Allele : Bace1<tm1Bux> beta-site APP cleaving enzyme 1; targeted mutation 1, Joseph D Buxbaum

Primary Identifier  MGI:3042562 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Bace1
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  The first exon was replaced with an IRES-beta-galactosidase expression cassette and a MC1-neomycin resistance gene. Western blot analysis of brain extracts confirmed the absence of protein product. Beta-galactosidase activity driven by the Bace1 promoter was detected.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele