Primary Identifier | MGI:3042562 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Bace1 |
Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The first exon was replaced with an IRES-beta-galactosidase expression cassette and a MC1-neomycin resistance gene. Western blot analysis of brain extracts confirmed the absence of protein product. Beta-galactosidase activity driven by the Bace1 promoter was detected. |