Primary Identifier | MGI:3042586 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rps6ka3 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 2 was disrupted by the insertion of a floxed neo cassette followed by 3 stop codons. The floxed cassette was removed via Cre-mediated excision, leaving a single loxP site followed by the stop codons. Western blot confirmed absence of protein in mutant cells. |