Primary Identifier | MGI:2183529 | Allele Type | Targeted |
Attribute String | Modified isoform(s) | Gene | Fgfr2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeted mutation is derived from Fgfr2tm3Lni by crossing to a cre-expressing line to remove the floxed neomycin cassette from intron 9. The engineered stop codon in exon 9 was left intact. The FgfrIIIc-specific absence of gene expression in homozygous mutant animals was verified by in situ hybridization. |