| Primary Identifier | MGI:3043746 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Igf2bp1 |
| Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Lexicon |
| molecularNote | A retroviral gene trap vector, containing a 5' LTR followed by a splice acceptor, beta-geo, PGK-puro, stop codons, a splice donor, and a 3' LTR, was inserted into intron 2. Insertion of the gene trap vector led to deletion of the second RNA recognition motif and the four K-homology modules, known to be essential for RNA binding, cytoplasmic granule formation, and subcytoplasmic localization. Normal transcript was undetected by RT-PCR analysis of homozygous mutant embryos. |
