| Primary Identifier | MGI:3043930 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Del(11Jmjd6-Mettl23)1Ysfk |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 2.8 kb segment including exons 1, 2 and part of exon 3 was replaced with a neo cassette via homologous recombination. Northern blot analysis confirmed the absence of RNA expression in homozygotes. A subsequent publication demonstrated that the neo cassette also replaced the first exon of the neighboring gene, Mettl23, located on the opposite strand. RT-PCR confirmed absence of Mettl23 mRNA in homozygous embryos. |
