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Allele : Aldh1a3<tm1Pcn> aldehyde dehydrogenase family 1, subfamily A3; targeted mutation 1, Pierre Chambon

Primary Identifier  MGI:3043945 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Aldh1a3
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neomycin cassette was inserted in the antisense orientation downstream of exon 9 while a third loxP site was inserted upstream of exon 8. Subsequently, the neomycin resistance gene was excised by transient transfection of properly target ES cells with a cre-expressing plasmid and leaving exons 8 and 9 which code for the catalytic site flanked by loxP sites.
  • mutations:
  • Insertion
  • synonyms:
  • Aldh1a3<L2>,
  • Aldh1a3<L2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories

Trail: Allele