Primary Identifier | MGI:3044171 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Amacr |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 1-3 were replaced with a neomycin selection cassette. Real-time PCR showed lack of transcript in mutant mice. Immunoblotting demonstrated lack of protein in mutant liver and kidney. |