| Primary Identifier | MGI:3043781 | Allele Type | Targeted |
| Gene | Pdpk1 | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | In order to ablate phosphatidylinositol 3,4,5-trisphoshate, 3 codons in exon 13 encoding arginine residues 472 through 474 were engineered to instead encoded leucince. A single loxP site remained downstream of exon 14 after a floxed neo cassette used for selection was excised via cre-mediated recombination. |
