| Primary Identifier | MGI:3044957 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Fgf15 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The coding region of exon 3, which is the last coding exon, was replaced with a neomycin selection cassette inserted by homologous recombination. RT-PCR analysis of homozygous mutant embryos indicated an absence of normal transcript, but identified a mutant transcript containing exons 1 and 2. The mutant transcript lacks exon 3 sequence and therefore does not encode the putative HSPG and FGFR binding sites. |
