Primary Identifier | MGI:3043589 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ercc5 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A stop codon was introduced at amino acid 811 and a loxP flanked PGK-neo cassette added via homologous recombination. This C-terminal truncation removed the last 360 amino acids. Northern blot analysis confirmed the presence of mRNA of normal size and amount. |