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Allele : Asic2<tm1.1Lzd> acid-sensing ion channel 2; targeted mutation 1.1, Michel Lazdunski

Primary Identifier  MGI:3043849 Allele Type  Targeted
Attribute String  Null/knockout Gene  Asic2
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was derived by crossing Accn1tm1Lzd mice with mice expressing Cre recombinase under the control of a cytomegalovirus promoter. This resulted in the excision of the exon encoding the second transmembrane domain causing a frameshift and truncating both known splice varients. Truncated mRNA was detectable by in situ hybridization but truncated protein was virtually absent.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • ASIC<->,
  • ASIC2<->,
  • ASIC2<->,
  • ASIC<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele