| Primary Identifier | MGI:3044290 | Allele Type | QTL |
| Gene | Tnfsf4 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| description | Homozygosity for C57BL/6J-derived alleles at both Ath1 and Ath2 confers susceptibility to atherosclerosis. Wang et al (J:140288) identified Ath1 in F2 animals homozygous for Apoetm1Unc. |
| molecularNote | This allele confers susceptibility to atherosclerosis and decreased HDL cholesterol levels on an atherogenic diet compared to BALB/cJ, C3H/HeJ, and SPRET/EiJ. This allele confers increased aortic lesion area in females on a high fat diet compared to C3H/HeJ. |
