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Allele : Ptges<tm1Lpa> prostaglandin E synthase; targeted mutation 1, Laurent P Audoly

Primary Identifier	MGI:3045658	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Ptges
Transmission	Germline	Strain of Origin	DBA/1LacJ
Is Recombinase	false	Is Wild Type	false

molecularNote

A neo was inserted to replace part of exon 1 and all of exon 2, corresponding to base pairs 35-256 of the cDNA sequence. Western blot indicated absence of protein in mutant macrophages.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
MPGES1-,
mPGES-1-,
MPGES1-,
mPGES-1-

earliestPublication:
Engblom D, et al. (2003) Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis. Nat Neurosci 6(11):1137-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

56 Publication categories

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