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Allele : Kit<tm2Ber> KIT proto-oncogene receptor tyrosine kinase; targeted mutation 2, Alan Bernstein
Primary Identifier  MGI:3045802 Allele Type  Targeted
Attribute String  Not Specified Gene  Kit
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A tyrosine to phenylalanine mutation (Y569F) was introduced into the juxtamembrane (Jx) domain in exon 11. Transient cre-mediated recombination removed an intronic floxed neo cassette located downstream of exon 11. Southern blot analysis demonstrated successful recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Kit<569F>,
  • Kit<569F>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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