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Allele : Tg(Pax2-cre)1Akg transgene insertion 1, Andrew K Groves

Primary Identifier  MGI:3046196 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Pax2-cre)1Akg
Strain of Origin  Not Specified Is Recombinase  true
Is Wild Type  false
molecularNote  A 121kb segment of the Pax2 gene which included 101 kb of sequence upstream of exon1, all of exons 1 and 2, part of exon 3, as well as introns 1 and 2, was modified by the insertion of IRES-cre into exon 2. Cre expression was demonstrated in the otic placode starting at the 6-7 somite stage. Cre expression also occurred in the midbrain-hindbrain boundary and the embryonic kidney. Two founders showed germline transmission of cre, and the line that displayed stronger cre mRNA expression was designated by MGI as line 1.
  • mutations:
  • Insertion
  • synonyms:
  • Pax2-Cre,
  • Pax2-Cre
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

1 Driven By

Trail: Allele

140 Publication categories

Trail: Allele