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Allele : Bub1b<tm1Jvd> BUB1B, mitotic checkpoint serine/threonine kinase; targeted mutation 1, Jan M A van Deursen
Primary Identifier  MGI:3046580 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Bub1b
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site, neo cassette, and cryptic exon were inserted between exons 5 and 6 and a second loxP site inserted 5' of exon 5 via homologous recombination. Western blot analysis confirmed decreased protein expression from this hypomorphic allele.
  • mutations:
  • Insertion
  • synonyms:
  • Bub1b<H>,
  • Bub1b<H>,
  • BubR1<H>,
  • BubR1<H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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26 Publication categories

Trail: Allele




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