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Allele : Hes7<tm2Kag> hes family bHLH transcription factor 7; targeted mutation 2, Ryoichiro Kageyama
Primary Identifier  MGI:3046536 Allele Type  Targeted
Attribute String  Not Specified Gene  Hes7
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An A to G transition mutation was introduced at nucleotide residue 118 in exon 1 converting a lysine into an arginine (K14R). This mutation increased the half-life of the protein from about 22 minutes to about 30 minutes without knocking out repressor activity. In situ analysis indicates that the mutant protein is expressed.
  • mutations:
  • Single point mutation
  • synonyms:
  • Hes7<tm2Rka>,
  • Hes7<118G>,
  • Hes7<tm2Rka>,
  • Hes7<118G>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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