| First Author | Ruggiero C | Year | 2015 |
| Journal | Mol Cell Endocrinol | Volume | 408 |
| Pages | 138-44 | PubMed ID | 25449416 |
| Mgi Jnum | J:223656 | Mgi Id | MGI:5660043 |
| Doi | 10.1016/j.mce.2014.10.022 | Citation | Ruggiero C, et al. (2015) How genomic studies have improved our understanding of the mechanisms of transcriptional regulation by NR5A nuclear receptors. Mol Cell Endocrinol 408:138-44 |
| abstractText | SF-1 and LRH-1 are transcription factors that belong to the NR5A family of nuclear receptors that both have an essential role during development. Recent studies at the genome-wide scale have enabled the characterization of the cistrome and transcriptome regulated by SF-1 and LRH-1 in different cell lines and tissues. Those studies have allowed us to make a significant leap forward in our understanding of the mechanisms of transcriptional regulation of NR5A nuclear receptors in stem cells and cancer. |
