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Allele : Itga6<tm1Son> integrin alpha 6; targeted mutation 1, Arnoud Sonnenberg

Primary Identifier  MGI:3050562 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Itga6
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An exon containing coding sequence specific to the A isoform was deleted by replacement with a loxP-flanked neomycin cassette, followed by cre-mediated recombination in ES cells. This resulted in a single loxP site in place of the exon, and led to the exclusive expression of the B isoform in all tissues where the A isoform was normally expressed.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • alpha6A-,
  • Itga6<loxP>,
  • Itga6<loxP>,
  • alpha6A-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele