| Primary Identifier | MGI:3051374 | Allele Type | Targeted |
| Gene | Hoxd | Transmission | Germline |
| Strain of Origin | 129S2/SvPas | Is Recombinase | false |
| Is Wild Type | false |
| description | Mutant mice were generated from TgH[d11/lac]Ge cells (the targeted D3 ES cells). |
| molecularNote | This allele involved the use of an embryonic stem cell line with a Hoxd11/lac/loxP reporter gene inserted 5' of Hoxd13. A floxed neo was inserted 3' to the Hoxd1 gene in the reverse orientation. Crossing with mice in which Cre is expressed in the germ line excised the neo and reversed the orientation of the larger floxed sequence. |
