Primary Identifier | MGI:3050869 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(MMTV-Erbb2)NF1Mul |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
description | Multiple transgenic lines were produced, including NA1 and NK1. |
molecularNote | This transgene contains the MMTV (mouse mammary tumor virus) promoter and a 4.6 kb cDNA from the rat Erbb2 (avian erythroblastosis B2) oncogene. The activated form of the gene is used in this construct, which differs from the wild-type allele by a point mutation, Val664Glu. Six transgenic lines were produced (NA, NB, NF, NK, NL and NM). |