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Allele : Tg(MMTV-Erbb2)NF1Mul transgene insertion NF1, William Muller

Primary Identifier  MGI:3050869 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(MMTV-Erbb2)NF1Mul
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
description  Multiple transgenic lines were produced, including NA1 and NK1.
molecularNote  This transgene contains the MMTV (mouse mammary tumor virus) promoter and a 4.6 kb cDNA from the rat Erbb2 (avian erythroblastosis B2) oncogene. The activated form of the gene is used in this construct, which differs from the wild-type allele by a point mutation, Val664Glu. Six transgenic lines were produced (NA, NB, NF, NK, NL and NM).
  • mutations:
  • Insertion
  • synonyms:
  • TG.NF,
  • MMTV-ErbB2<Act>,
  • TG.NF,
  • MMTV-ErbB2<Act>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele