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Allele : Rabgef1<tm2Glli> RAB guanine nucleotide exchange factor (GEF) 1; targeted mutation 2, Stephen J Galli

Primary Identifier  MGI:3051238 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rabgef1
Transmission  Germline Strain of Origin  WBB6F1
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with an IRES and floxed PGK-neo cassette. Southern blot confirmed recombination and RT-PCR indicated no mRNA in mutant pups. Immunoblot demonstrated lack of expression of the full-length protein in fetal liver mast cells.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • Rabgef1<->,
  • Rabgef1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele